ONCOLOGY

 

Novel targets in the following pathways

  • 1. Immunotherapy approaches (specifically those affecting immune-checkpoint and immune-stimulatory pathways, and T-cell redirection)
  • 2. Tumor microenvironment (specifically those that target angiogenesis and activated stroma)
  • 3. Novel cancer cell signaling and antibody-drug conjugate (ADC) targets
  • 4. Tumor metabolism
  • 5. Epigenetics

Emphasis on the following cancer indications

  • 1.Breast malignancies
  • 2.Heme malignancies

Out of Scope

  • 1. Cell-based therapies, and/or approaches requiring ex vivo manipulation of patient tissue(s)
  • 2.Re-formulations of cytotoxics
  • 3. Preventive care
  • 4.Supportive care
  • 5.Gene therapy